| 523 |
Acute Sulfur Mustard Exposure |
Bronchial Epithelium |
total cell count |
UP |
Case-Control |
Healthy Control |
Acute Sulfur Mustard Exposure |
<0.05 |
|
in vivo |
Rattus norvegicus |
BAL cells |
Cell |
7 |
9 |
Enzyme-linked immunosorbent assay (ELISA) |
NM |
| 1685 |
Acute Sulfur Mustard Exposure |
Bronchial Epithelium |
AGER |
UP |
Case-Control |
Healthy Control |
Acute Sulfur Mustard Exposure |
<0.05 |
|
in vivo |
Rattus norvegicus |
advanced glycation end product - RAGE |
Protein |
7 |
9 |
Enzyme-linked immunosorbent assay (ELISA) |
NM |
| 2852 |
Acute Sulfur Mustard Exposure |
Whole Lung |
SERPINE1 |
UP |
Case-Control |
Healthy Control |
Acute Sulfur Mustard Exposure |
<0.001 |
|
in vivo |
Rattus norvegicus |
procoagulant protein |
Protein |
2 |
9 |
Enzyme-linked immunosorbent assay (ELISA) |
NM |
| 2853 |
Acute Sulfur Mustard Exposure |
Whole Lung |
SERPINE1 |
UP |
Case-Control |
Healthy Control |
Acute Sulfur Mustard Exposure |
<0.05 |
|
in vivo |
Rattus norvegicus |
procoagulant protein |
Protein |
2 |
9 |
Enzyme-linked immunosorbent assay (ELISA) |
NM |
| 2856 |
Acute Sulfur Mustard Exposure |
Bronchial Epithelium |
SFTPD |
UP |
Case-Control |
Healthy Control |
Acute Sulfur Mustard Exposure |
<0.05 |
|
in vivo |
Rattus norvegicus |
|
Protein |
7 |
9 |
Enzyme-linked immunosorbent assay (ELISA) |
NM |
| 2857 |
Acute Sulfur Mustard Exposure |
Bronchial Epithelium |
SFTPD |
UP |
Case-Control |
Healthy Control |
Acute Sulfur Mustard Exposure |
<0.05 |
|
in vivo |
Rattus norvegicus |
surfactant protein-D |
Protein |
7 |
9 |
Enzyme-linked immunosorbent assay (ELISA) |
NM |
| 2988 |
Acute Sulfur Mustard Exposure |
Whole Lung |
TGFB1 |
UP |
Case-Control |
Healthy Control |
Acute Sulfur Mustard Exposure |
<0.05 |
|
in vivo |
Rattus norvegicus |
transforming growth factor-b |
Protein |
2 |
9 |
Enzyme-linked immunosorbent assay (ELISA) |
NM |
| 2989 |
Acute Sulfur Mustard Exposure |
Whole Lung |
TGFB1 |
NC |
Case-Control |
Healthy Control |
Acute Sulfur Mustard Exposure |
NM |
|
in vivo |
Rattus norvegicus |
transforming growth factor-b |
Protein |
2 |
9 |
Enzyme-linked immunosorbent assay (ELISA) |
NM |
| 3121 |
Acute Sulfur Mustard Exposure |
Bronchial Epithelium |
MMP9 |
UP |
Case-Control |
Healthy Control |
Acute Sulfur Mustard Exposure |
<0.05 |
|
in vivo |
Rattus norvegicus |
matrix metalloproteinase-9 |
Protein |
7 |
9 |
Enzyme-linked immunosorbent assay (ELISA) |
NM |
| 3122 |
Acute Sulfur Mustard Exposure |
Bronchial Epithelium |
HMGB1 |
UP |
Case-Control |
Healthy Control |
Acute Sulfur Mustard Exposure |
<0.05 |
|
in vivo |
Rattus norvegicus |
high mobility group box protein-1 |
Protein |
7 |
9 |
Enzyme-linked immunosorbent assay (ELISA) |
NM |
| 4627 |
Acute Sulfur Mustard Exposure |
Bronchial Epithelium |
macrophage |
NC |
Case-Control |
Healthy Control |
Acute Sulfur Mustard Exposure |
<0.05 |
|
in vivo |
Rattus norvegicus |
Alveolar macrophages |
Cell |
7 |
9 |
histopathology |
NM |
| 4628 |
Acute Sulfur Mustard Exposure |
Bronchial Epithelium |
alveolar wall thickening |
UP |
Case-Control |
Healthy Control |
Acute Sulfur Mustard Exposure |
<0.05 |
|
in vivo |
Rattus norvegicus |
Thickening of alveolar wall |
Phenotype |
7 |
9 |
histopathology |
NM |
| 4629 |
Acute Sulfur Mustard Exposure |
Bronchial Epithelium |
epithelial attenuation |
UP |
Case-Control |
Healthy Control |
Acute Sulfur Mustard Exposure |
<0.05 |
|
in vivo |
Rattus norvegicus |
Epithelial attenuation |
Phenotype |
7 |
9 |
histopathology |
NM |
| 4630 |
Acute Sulfur Mustard Exposure |
Bronchial Epithelium |
epithelial degeneration |
UP |
Case-Control |
Healthy Control |
Acute Sulfur Mustard Exposure |
<0.05 |
|
in vivo |
Rattus norvegicus |
Epithelial degeneration/necrosis |
Phenotype |
7 |
9 |
histopathology |
NM |
| 4657 |
Acute Sulfur Mustard Exposure |
Bronchial Epithelium |
epithelial degeneration |
NC |
Case-Control |
Healthy Control |
Acute Sulfur Mustard Exposure |
<0.05 |
|
in vivo |
Rattus norvegicus |
Epithelial degeneration/necrosis |
Phenotype |
7 |
9 |
histopathology |
NM |
| 4754 |
Acute Sulfur Mustard Exposure |
Bronchial Epithelium |
epithelial degeneration |
NC |
Case-Control |
Healthy Control |
Acute Sulfur Mustard Exposure |
<0.05 |
|
in vivo |
Rattus norvegicus |
Epithelial degeneration/necrosis |
Phenotype |
7 |
9 |
histopathology |
NM |
| 4781 |
Acute Sulfur Mustard Exposure |
Bronchial Epithelium |
epithelial hyperplasia/metaplasia |
NC |
Case-Control |
Healthy Control |
Acute Sulfur Mustard Exposure |
<0.05 |
|
in vivo |
Rattus norvegicus |
Epithelial hyperplasia/metaplasia |
Phenotype |
7 |
9 |
histopathology |
NM |
| 4827 |
Acute Sulfur Mustard Exposure |
Whole Lung |
lung resistance |
UP |
Case-Control |
Healthy Control |
Acute Sulfur Mustard Exposure |
<0.0001 |
|
in vivo |
Rattus norvegicus |
Total Lung Resistance |
Phenotype |
2 |
9 |
NM |
NM |
| 4936 |
Acute Sulfur Mustard Exposure |
Whole Lung |
newtonian resistance |
NC |
Case-Control |
Healthy Control |
Acute Sulfur Mustard Exposure |
NM |
|
in vivo |
Rattus norvegicus |
Newtonian Resistance |
Phenotype |
2 |
9 |
NM |
NM |
| 4976 |
Acute Sulfur Mustard Exposure |
Bronchial Epithelium |
epithelial metaplasia |
UP |
Case-Control |
Healthy Control |
Acute Sulfur Mustard Exposure |
<0.05 |
|
in vivo |
Rattus norvegicus |
Epithelial metaplasia/regeneration |
Phenotype |
7 |
9 |
histopathology |
NM |
| 4977 |
Acute Sulfur Mustard Exposure |
Bronchial Epithelium |
fibrin |
NC |
Case-Control |
Healthy Control |
Acute Sulfur Mustard Exposure |
<0.05 |
|
in vivo |
Rattus norvegicus |
Fibrin |
Phenotype |
7 |
9 |
histopathology |
NM |
| 4998 |
Acute Sulfur Mustard Exposure |
Bronchial Epithelium |
honeycomb formation |
NC |
Case-Control |
Healthy Control |
Acute Sulfur Mustard Exposure |
<0.05 |
|
in vivo |
Rattus norvegicus |
Honeycomb formation |
Phenotype |
7 |
9 |
histopathology |
NM |
| 5026 |
Acute Sulfur Mustard Exposure |
Bronchial Epithelium |
inflammation |
NC |
Case-Control |
Healthy Control |
Acute Sulfur Mustard Exposure |
<0.05 |
|
in vivo |
Rattus norvegicus |
Inflammation |
Phenotype |
7 |
9 |
histopathology |
NM |
| 5177 |
Acute Sulfur Mustard Exposure |
Whole Lung |
tissue damping |
UP |
Case-Control |
Healthy Control |
Acute Sulfur Mustard Exposure |
<0.01 |
|
in vivo |
Rattus norvegicus |
Tissue Damping |
Phenotype |
2 |
9 |
NM |
NM |
| 5496 |
Acute Sulfur Mustard Exposure |
Bronchial Epithelium |
peribronchial inflammation |
UP |
Case-Control |
Healthy Control |
Acute Sulfur Mustard Exposure |
<0.05 |
|
in vivo |
Rattus norvegicus |
Peribronchial inflammation |
Phenotype |
7 |
9 |
histopathology |
NM |
| 5497 |
Acute Sulfur Mustard Exposure |
Bronchial Epithelium |
peribronchial inflammation |
UP |
Case-Control |
Healthy Control |
Acute Sulfur Mustard Exposure |
<0.05 |
|
in vivo |
Rattus norvegicus |
Peribronchial inflammation |
Phenotype |
7 |
9 |
histopathology |
NM |
| 5498 |
Acute Sulfur Mustard Exposure |
Bronchial Epithelium |
proteinaceous fluid |
NC |
Case-Control |
Healthy Control |
Acute Sulfur Mustard Exposure |
<0.05 |
|
in vivo |
Rattus norvegicus |
Proteinaceous fluid |
Phenotype |
7 |
9 |
histopathology |
NM |
| 6163 |
Acute Sulfur Mustard Exposure |
Whole Lung |
lung compliance |
DOWN |
Case-Control |
Healthy Control |
Acute Sulfur Mustard Exposure |
<0.0001 |
|
in vivo |
Rattus norvegicus |
Total Lung Compliance |
Phenotype |
2 |
9 |
NM |
NM |
| 6558 |
Acute Sulfur Mustard Exposure |
Bronchial Epithelium |
septal defects |
NC |
Case-Control |
Healthy Control |
Acute Sulfur Mustard Exposure |
<0.05 |
|
in vivo |
Rattus norvegicus |
Septal defects |
Phenotype |
7 |
9 |
histopathology |
NM |
| 6561 |
Acute Sulfur Mustard Exposure |
Bronchial Epithelium |
edema |
NC |
Case-Control |
Healthy Control |
Acute Sulfur Mustard Exposure |
<0.05 |
|
in vivo |
Rattus norvegicus |
Peribronchial edema |
Phenotype |
7 |
9 |
histopathology |
NM |
| 6562 |
Acute Sulfur Mustard Exposure |
Bronchial Epithelium |
edema |
NC |
Case-Control |
Healthy Control |
Acute Sulfur Mustard Exposure |
<0.05 |
|
in vivo |
Rattus norvegicus |
Peribronchial edema |
Phenotype |
7 |
9 |
histopathology |
NM |
| 6563 |
Acute Sulfur Mustard Exposure |
Bronchial Epithelium |
edema |
UP |
Case-Control |
Healthy Control |
Acute Sulfur Mustard Exposure |
<0.05 |
|
in vivo |
Rattus norvegicus |
Perivascular edema and inflammatory cells |
Phenotype |
7 |
9 |
histopathology |
NM |
| 6565 |
Acute Sulfur Mustard Exposure |
Bronchial Epithelium |
pulmonary fibrosis |
NC |
Case-Control |
Healthy Control |
Acute Sulfur Mustard Exposure |
<0.05 |
|
in vivo |
Rattus norvegicus |
Fibrosis |
Phenotype |
7 |
9 |
histopathology |
NM |
| 6643 |
Acute Sulfur Mustard Exposure |
Bronchial Epithelium |
total protein level |
UP |
Case-Control |
Healthy Control |
Acute Sulfur Mustard Exposure |
<0.05 |
|
in vivo |
Rattus norvegicus |
BAL total protein |
Protein |
7 |
9 |
Enzyme-linked immunosorbent assay (ELISA) |
NM |